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Even if the holes are placed exactly the same the chainrings are shaped to fit only in 6800, you may need to file it to make it fit. Also, the small chainring on GRX it's not 110 bcd, it's smaller,so you wouldn't be able to use a pair and probably it will shift pretty badly. And it would look like ass.
Anyways, 48t is plenty for anything up to 70kph, and probably a lot more useful than a 53 for the average cyclist -
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I don't see how the power meter would be able to isolate your watts from the huge torque of the e-bike.