We had a pair of sisters when I was a lad. They lived in a hutch in the shed which had a gutter pipe tunnel to a large play pen outside and were handled pretty much daily.
They were spayed, as females don't do well if they don't mate, they stay in heat and die of anemia.
They didn't smell too bad, and my dad found a change of food early on which improved things.
From what I remember they were very tidy and only did toilet business in the outside cat litter tray.