speaking from experience and having been at a regular riding weight of 120-130 KGS for most of the last 15 years, I have had significant success riding on London streets with the following:
Road - Campy Record hubs laced 3 cross to DT Swiss RR 585 rims
Fixie - Phil Wood 32h hubs laced 3 cross to H Plus Son SL 42 rims
Fixie - Royce 32h hubs laced 3 cross to H Plus son archetype rims
All used either SAPIM or DT SWISS spokes
The bottom line is quality works....