if you want speed and reliability - go for firewire
if you want compatibility and portability - go for usb
on paper usb is faster, but this is only measured at the peak of the data transfer rate. firewire has been shown to average a much faster speed over a sustained period.
2.5" drives are great and really portable, but use slower disk speeds than 3.5" drives.
you can get some 2.5" drives which have a usb cable for the power supply, but actually transfer the data with firewire. maybe this is a good compromise although you'll still have a slower disc speed.
if you want speed and reliability - go for firewire
if you want compatibility and portability - go for usb
on paper usb is faster, but this is only measured at the peak of the data transfer rate. firewire has been shown to average a much faster speed over a sustained period.
2.5" drives are great and really portable, but use slower disk speeds than 3.5" drives.
you can get some 2.5" drives which have a usb cable for the power supply, but actually transfer the data with firewire. maybe this is a good compromise although you'll still have a slower disc speed.