The fit of the frame will make the biggest impact on your comfort, then contact points that work for you including tyres at an appropriate pressure.
i have a new pair of continental gatorskins that i will be using for this new bike. i had continental ultrasports before these and vittoria rubino before that. all of them were 23c and i kept them at around 110-115psi
as far as frame fit i am 5"10 with a 30" inseam. my last frame was a 56cm and it seemed to fit well. i am looking at the medium size for the Lo Pro
i have a new pair of continental gatorskins that i will be using for this new bike. i had continental ultrasports before these and vittoria rubino before that. all of them were 23c and i kept them at around 110-115psi
as far as frame fit i am 5"10 with a 30" inseam. my last frame was a 56cm and it seemed to fit well. i am looking at the medium size for the Lo Pro