That is effectively what I have done with the CC. 1x10 setup for mid-range tours, then I have a Surly 135mm hub laced to an OpenPro rim for when I want SS or Fixed. 1 Bike - 3 modes.
Dealing with the shifter cable is the only annoyance. I use a bar-end shifter, so that means re-wrapping. Or what I might do is just get a longer stem and a riser with levers and grips. Then just transplant the whole cockpit and cables when I swap. Any alternative recommendations welcome.